In Ladies with normal codeine metabolism (standard CYP2D6 exercise), the amount of codeine secreted into human milk is low and dose-dependent. There is not any info on the effects in the codeine on milk generation.
11)]. Observe patients for indications of urinary retention or minimized gastric motility when promethazine HCl and codeine phosphate oral Answer is utilised concomitantly with anticholinergic medicine.
Hazard Summary Promethazine HCl and codeine phosphate oral Alternative is just not encouraged for use in Expecting Gals, together with during or straight away ahead of labor.
Analgesics, also called ache killers, are different types of medications utilised To ease soreness. Many of these prescription drugs can be utilized to take care of discomfort throughout clinical procedures likewise.
Get in touch with regional state professional licensing board or point out controlled substances authority for info on how to prevent and detect abuse or diversion of this product.
No unique drug interaction reports have been done with promethazine HCl and codeine phosphate oral Resolution.
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As an example, many documented instances of Dying transpired while in the write-up-operative time period pursuing tonsillectomy and/or adenoidectomy, and a lot of of the youngsters had evidence of currently being extremely-fast metabolizers of codeine. Furthermore, children with obstructive rest apnea who will be treated with codeine for write-up-tonsillectomy and/or adenoidectomy discomfort may very well be notably sensitive to its respiratory depressant influence. Due to the threat of life-threatening respiratory melancholy and death:
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Clinical Criteria Infants subjected to promethazine HCl and codeine phosphate oral Remedy through breast milk need to be monitored for extra sedation and respiratory melancholy.
Many research analyzing using promethazine in pregnancy did not uncover an association with an elevated danger of click here congenital anomalies. During the handful of experiments reporting an Affiliation, no constant sample of malformations was pointed out. Many of the experiments, each constructive and detrimental, were being restricted by smaller sample sizing, remember bias and absence of knowledge concerning dose and timing of exposure.
Your Health care provider may possibly do blood assessments to check for adrenal gland challenges. Connect with your Health care supplier immediately When you have any of those signs and symptoms:
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