5.eighteen Significant Hypotension Promethazine HCl and codeine phosphate oral solution could bring about significant hypotension which includes orthostatic hypotension and syncope in ambulatory patients. There's improved hazard in people whose capacity to maintain blood pressure has now been compromised by a decreased blood quantity or concurrent

In Ladies with normal codeine metabolism (standard CYP2D6 exercise), the amount of codeine secreted into human milk is low and dose-dependent. There is not any info on the effects in the codeine on milk generation.11)]. Observe patients for indications of urinary retention or minimized gastric motility when promethazine HCl and codeine phosphate or